Background: Asthma is one of the major public health problems for the developed and developing countries. The use of Allopathic system of medicines provides only short term symptom relief to patients. At times, short term or no significant relief from the allopathic medicines is followed by several side effects. Methods: This study was carried out at among 30 patients diagnosed with fungus-induced obstructive airway disease who visited the OPD of own private practice at Johnpur UP, for its cure. This study tries to correlate the symptoms observed among the population studied and the effectiveness of homoeopathic medicines. The record of medicines prescribed by doctor was also considered in the study. Thirty patients with written consent for participations were enrolled for follow up of seven days during medication. Twelve predefined homoeopathic medicines were selected for the study Results: More than 50% percent of patients following the prescribed medications, reported improvement in health. Only, 13.3% of patients were completely cured and 10% showed marked improvement. Conclusions: Homoeopathic medicines are effective in treatment of fungus-induced obstructive airway disease. Proper observation of the symptoms and choosing the proper medicine provides relief to the patient from the disease under study. There is a further need for study with a larger cohort. Keywords: homoeopathy, fungus-induced asthma, allergic asthma, seasonal allergy