Root canal therapy if one of the most common dental procedures employed days in routine dental practice. Its success is dependent upon a number of factors, among which, one is root canal irrigation. Sodium hypochloride is the most commonly used endodontic irrigant, despite limitations. None of the presently available root canal irrigants satisfy the requirements of ideal root canal irrigant. Hence; in the present review, we aim to highlight some of the important aspects of roots anal irrigation process. Key words: Irrigation, Root canal Abstract