Background:Pakistan currently has two forms of pre medical educational setup prevalent. FSc. relies heavily on rote memorization while A-levels, involves Problem Based Learning (PBL) and critical thinking. The choices of premedical education have impact on learning methodologies amongst students in their MBBS career pathway. Methodology: A cross sectional survey conducted at Fatima Memorial Hospital College of Medicine and Dentistry, Lahore during December 2014 to March 2015. A non-probability consecutive sampling technique was used to select 139 first year MBBS students. A self administered questionnaire was used to collect data. Data was analyzed using SPSS 20.Chi square test for association and statistical significance was applied and p value of > 0.05 was considered significant. Results: Among 139 students, 45(32%) were males and 94(67%) were females. Out of these 139 students, 68.8% of the males and 74.9% of females opted for FSc. Around 76% of Pakistani nationals had studied in FSc system while 24% had gone for A ‘levels as compared to foreign nationals (p value 0.018). Among 108 students who preferred problem based learning 71.3% had done FSc and 28.7% had done A ‘levels (p value 0.213).Seventy eight percent of the students want to stay in Pakistan after completion of their studies have done FSc (p value 0.028). Conclusion: Choice of premedical education affects learning methodologies and decision pursuing medical career abroad. Keywords: Learning , Premedical Education, Memorization