Background: The spleen is one of the most commonly injured intra-abdominal organs. The diagnosis and prompt management of potentially life-threatening hemorrhage is the primary goal. The present study was conducted to analyze the cases of splenectomy in study population. Materials & Methods: The present study was conducted in the department of general surgery on 120 patients of both genders. General information such as name, age, gender etc. was recorded. In all patients, causes of spleen injury were evaluated. Results: Out of 120 patients, males were 65 and females were 55. The difference was non- significant (P- 0.5). Age group 21-30 years had 9 males and 5 females, 31-40 years had 10 males and 12 females, 41- 50 years had 26 males and 18 females, >50 years had 20 males and 20 females. The difference was significant (P- 0.01). Common causes of spleen injury were blunt trauma (30), traffic accident (35), falling down (15), penetrating injury (25) and gunshot (15). The difference was significant (P- 0.01). Conclusion: Spleen is the delicate organ which is susceptible to injuries. The common causes are penetrating injuries, road accidents, falling down, gun shot etc. Key words: Gunshot, Spleen, Trauma